Collecting vaccine pipeline data

Vaccines can be powerful tools for preventing outbreaks of infectious diseases becoming humanitarian crises. However, developing these vaccines requires significant investment and evidence on what it would cost to successfully develop an effective vaccine against such diseases are scarce.

We assessed 224 vaccine candidates from preclinical through to phase 2 for 11 priority epidemic infectious diseases. Out study showed that the cost of progressing at least one vaccine through to the end of phase 2a for each of the 11 diseases would cost a minimum of $2.8-$3.7 billion ($1·2 billion–$8·4 billion range). By comparison, the global cost of a moderately severe to severe pandemic is thought to be as much as $570 billion.

You can read the full research paper in The Lancet Global Health.

We are continuing to map available vaccine candidates against emerging infectious disease and their associated costs, concentrating on the vaccine research and development pipelines for diseases listed in the World Health Organisation’s R+D Blueprint (ie, Crimean Congo haemorrhagic fever, Lassa fever, MERS-CoV, Severe Acute Respiratory syndrome, Nipah, Rift Valley Fever,  Zika, Ebola and Marburg).

We are also mapping vaccine candidates for other diseases that have epidemic potential not included in the R+D Blueprint priority list, including Chikungunya and Severe Fever with Thrombocytopaenia Syndrome.

If you are working within this space and would like to contribute information about your vaccine candidate against epidemic disease threats, please email us [email protected].